Vitamin C Injections Slow Growth Potential Tumor
23 Aug
Injection of high doses of vitamin C, also known as ascorbate or ascorbic acid, reduced tumor weight and growth rate up to 50% in rat brain samples, ovarian cancer and pancreas, said researchers from the U.S. National Institutes of Health (NIH).
The researchers track the anti-cancer effects of ascorbate on the formation of hydrogen peroxide in the extracellular fluid surrounding the tumors. Normal cells unaffected. The results were published in the journal planned Proceedings of the National Academy of Sciences.
Monitoring for certain natural psychological adjust the amount of ascorbate absorbed by the body when the substance is consumed orally. To pass the normal monitoring, the NIH scientists injected ascorbate into the veins or abdominal cavities of rodents with tumors of the pancreas, ovaries and brain aggressive.
By doing that, they are able to send a high dose of ascorbate, as much as 4 grams per kilogram in weight every day.
“At the high dose injection, we expect to see activity such as drugs that may be useful in the treatment of cancer,” said Mark Levine, lead author of the study.
Vitamin C plays an important role in health, and the deterioration of these vitamins cause prolonged bleeding gums disease and ultimately death. Vitamin C may also act as anti-oxidants, protecting cells from free radical damage.
However, the NIH researchers are testing the idea that ascorbate, when injected at high doses, may have prooksidan, and not the anti-oxidant activity. Prooksidan will drive the formation of free radicals and hydrogen peroxide, which, according to scientists hypothesized, might kill tumor cells.
In laboratory experiments on 43 cancer cell lines and 5 normal cells, the researchers found that high concentrations of ascorbate had anticancer effects in 75% of cancer cells lines tested, and at the same time not affecting normal cells. In their writings, the researchers also showed that these high ascorbate concentrations could be achieved in humans.
The team then tested ascorbate injections in rats that experienced a decline of immune system also has a brain tumor, pancreatic and ovarian spread.
The ascorbate injections reduced tumor weight and growth to 41 to 53%.
“Pre-clinical data that provide a strong basis for achieving the first pharmacologic ascorbate in cancer treatment in humans,” the researchers concluded that
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